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KMID : 0374920140350010107
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Inje Medical Journal
2014 Volume.35 No. 1 p.107 ~ p.115
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Acute Pneumonia Due to Mycobacterium Avium in a Patient with Chronic Obstructive Pulmonary Disease
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Lee Hyun-Woo
Shin Jung-A
Jung Joo-Hyuk
Koo Hyun-Kyung
Park Hye-Kyeong
Lee Sung-Soon
Jung Hoon
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Abstract
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We report a rare case of acute pneumonia caused by Mycobacterium avium in a 73-year-old man who had been diagnosed with frequent exacerbation of severe chronic obstructive pulmonary disease (COPD). The Mycobacterium avium-intracellulare complex (MAC) is the most common pathogen in pulmonary disease caused by nontuberculous mycobacteria (NTM). MAC pulmonary diseases usually have the insidious nature. However, the patient was initially diagnosed with bacterial pneumonia due to pneumonic infiltration in the right upper lung field of chest X-ray and high-grade fever. After mycobacteria were detected from sputum smear a few days later, he was prescribed with anti-tuberculous chemotherapy. Despite the anti-tuberculous treatment, there was no improvement in the symptoms of fever and pulmonary infiltration. A few days later, the polymerase chain reaction was positive for NTM and Mycobacterium avium grew in culture of three sputum specimens. We chose clarithromycin-based anti-MAC chemotherapy. The pneumonic infiltrates almost disappeared within two months.
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KEYWORD
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Mycobacterium avium, Mycobacterium avium-intracellulare infection, Mycobacterium avium complex, Pneumonia, Nontuberculous mycobacteria
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